OLMEDINE 20/5 MG 28 TABLETS

OLMEDINE 20/5 MG 28 TABLETS
Product Description
 
OLMEDINE 20/5 MG FILM-COATED TABLET 28'S
(20 mg Olmesartan Medoxomil / 5 mg Amlodipine Besilate)
Indication
Olmedine contains two substances called olmesartan medoxomil and amlodipine (as amlodipine besilate). both of these substances help to control high blood pressure.
Olmesartan medoxomil belongs to a group of medicine called angiotensin-II receptor antagonists” which lower blood pressure by relaxing the blood vessels.
Amlodipine belongs to a group of substances called “calcium channel blockers”. Amlodipine stops calcium from moving into the blood vessel wall which stops the blood vessels from tightening thereby also reducing blood pressure.
The actions of both these substances contribute to stopping the tightening of blood vessels, so that blood vessels relax and blood pressure decreases. Olmedine is used for the treatment of high blood pressure in patients whose blood pressure is not controlled enough with either olmesartan medoxomil or amlodipine alone.
Dosage and administration
Olmedine can be taken with or without food. Swallow the tablet with some fluid (such as one glass of water). If possible, take your daily dose at the same time each day, for example at breakfast time. Grapefruit juice and grapefruit should not be consumed by people who are taking Olmedine. This is because grapefruit and grapefruit juice can lead to an increase in the blood levels of the active ingredient amlodipine, which can cause an unpredictable increase in the blood pressure lowering effect of Olmedine.
Always take this medicine exactly as your doctor or pharmacist has told you. Check with your doctor or pharmacist if you are not sure.
The recommended dose of Olmedine is one tablet per day.
The tablets can be taken with or without food. Swallow the tablet with some fluid (such as a glass of water).
The tablet should not be chewed. Do not take them with grapefruit juice.
If possible, take your daily dose at the same time each day, for example at breakfast time
Possible side effect
Possible side effects Like all medicines, this medicine can cause side effects, although not everybody gets them. If they do occur, they are often mild and do not require treatment to be stopped.
Although not many people may get them, the following two side effects can be serious:
Allergic reactions, that may affect the whole body, with swelling of the face, mouth and/or larynx (voice box) together with itching and rash may occur during treatment with olmesartan medoxomil/amlodipine. If this happens stop taking Olmedine and talk to your doctor immediately. Olmesartan medoxomil/amlodipine can cause the blood pressure to fall too low in susceptible individuals or as the result of an allergic reaction. This could cause severe light-headedness or fainting. If this happens stop taking Olmedine, talk to your doctor immediately and lie down flat.
Other possible side effects with olmesartan medoxomil/amlodipine:
Common (may affect less than 1 in 10 people): Dizziness; headache; swelling of ankles, feet, legs, hands, or arms; tiredness.
Uncommon (may affect less than 1 in 100 people): Dizziness on standing up; lack of energy; tingling or numbness of hands or feet; vertigo; awareness of heart beat; fast heart beat; low blood pressure with symptoms such as dizziness, light-headedness; difficult breathing; cough; nausea; vomiting; indigestion; diarrhoea; constipation; dry mouth, upper abdominal pain; skin rash; cramps; pain in arms and legs; back pain; feeling more of an urge to pass urine; sexual inactivity; inability to get or maintain an erection; weakness. Some changes in blood test results have also been seen and include the following: increased as well as decreased blood potassium levels, increased blood creatinine levels, increased uric acid levels, increases in a test of liver function (gamma glutamyl transferase levels).
Rare (may affect less than 1 in 1,000 people): Drug hypersensitivity; fainting; redness and warm feeling of the face; red itchy bumps (hives); swelling of face. Side effects reported with use of olmesartan medoxomil or amlodipine alone, but not with Olmedine or in a higher frequency: Olmesartan medoxomil Common (may affect less than 1 in 10 people): Bronchitis; sore throat; runny or stuffy nose; cough; abdominal pain; stomach flu; diarrhoea; indigestion; nausea; pain in the joints or bones; back pain; blood in the urine; infection of the urinary tract; chest pain; flu-like symptoms; pain.